Affordable Access to Trikafta® for Cystic Fibrosis is Finally in Sight - Latest Updates in 2025

Summary - This blog shares the latest updates on affordable access to Trikafta® for cystic fibrosis as of Nov 2025. It explains the new Bangladesh generic launch, why prices in the United States remain high, and how MedsPartner will help patients access safe and lower-cost options through compliant personal import.

Cystic fibrosis is a genetic condition that damages the lungs and digestive system. While effective treatments are available, they are out of reach for many families because of the high price tag. Trikafta® has improved outcomes and cystic fibrosis life expectancy for many patients. But for years, high costs and limited availability have restricted access. This is finally changing! A Bangladesh manufacturer is set to launch a quality-assured generic at a fraction of the branded drug's price. MedsPartner plans to make this option reachable through a compliant pathway that protects patient safety. Here’s everything patients and caregivers should know about the upcoming launch.

What is Trikafta® and how does it work?

Trikafta® is a cystic fibrosis therapy that helps restore normal function of the faulty CFTR protein. It treats eligible patients aged 2 or more with at least one F508del or another responsive mutation.

The combination contains elexacaftor, tezacaftor and ivacaftor. Ivacaftor acts as a potentiator that improves chloride flow through CFTR channels. Tezacaftor and elexacaftor help the protein fold and traffic to the cell surface. Together, they improve lung function and reduce symptoms. 

Why is Trikafta® so expensive?

Without solid insurance coverage, most families cannot afford the high prices of Trikafta due to brand monopoly and patent protection.

84 tablets of Trikafta cost ~USD 27,000 in the US, making the annual treatment as high as USD 300,000. Even when copay cards lower out-of-pocket costs for some people, many families face denials or high deductibles that make treatment inaccessible.

Trikafta® access updates in 2025

A generic version of the medicine was announced for launch in Bangladesh, potentially cutting the annual price for adults to about USD 12,000 and for children to about USD 6,000. Once launched, this affordable generic alternative to Trikafta® can also be accessed by patients across the globe through compliant personal importation.

Is the new generic of Trikafta® safe?

Yes! Approved generics contain the same active ingredient and show similar safety and effectiveness as the branded med. 

MedsPartner makes sure of this by sourcing only from FDA-approved or EMA-approved manufacturers, who meet strict global quality standards. Every order comes with batch details and manufacturer info, so you can be confident about the medicine’s safety.

Can I legally import the soon-to-be-launched generic of Trikafta® into my country?

Many countries allow personal import of medicines for non-commercial use in limited quantities. MedsPartner supports compliant personal import by guiding you on the documents your local regulations require, and sourcing from vetted manufacturers after thorough document verification.

How much could I save by switching from branded Trikafta® to the generic?

The upcoming generic version of Trikafta® shall offer about 95% savings compared to the branded drug price in the United States.  This can bring massive savings and real hope to patients around the globe.

When will MedsPartner make this generic of Trikafta® available?

The Bangladesh generic is about to launch soon. MedsPartner plans to list it within a few months. Please write to us on support@medspartner.com and our team will send you the latest updates on the generic’s availability.

What if insurance denies Trikafta® or the copay is still very high?

Many families face plan exclusions, step-therapy rules, or high copay limits. Your doctor can support you by submitting an appeal. The Trikafta Patient Support Program can help some individuals, but many may not be eligible.

To avoid treatment interruptions, you can explore a personal importation of the quality-assured generic through MedsPartner.

Frequently asked questions about Trikafta® access

Q1. How much does Trikafta® cost in the US and how does that compare with the Bangladesh generic?

A. In the US, the price of Trikafta is nearly USD 300,000 per year. The Bangladesh generic shall cost ~USD 12,000 for adults and ~USD 6,000 for children per year.

Q2. Is the generic of Trikafta® as effective as the brand when sourced through MedsPartner?

A. Generics have the same active ingredients and strengths and are bioequivalent when made by quality-assured manufacturers. MedsPartner works only with FDA/EMA approved manufacturers and our stringent quality measures ensure that the drugs you receive are as safe and effective as their branded counterparts.

Q3. How does the named patient import process for Trikafta® work?

A. Once the medicine is live on medspartner.com, you can place an order seamlessly on the website. You will have to provide a valid prescription and documents as per your country's regulations. MedsPartner shall verify the same and ship your medicines to your doorstep after sourcing them from an accredited manufacturer.

Q4. I am a doctor. How can I order generic Trikafta for my patients?

A. As a doctor, you can help your patients access affordable Trikafta generics through MedsPartner's compliant import pathway, once the medicine is available on our website. Contact MedsPartner at support@medspartner.com to discuss how to place orders for your patients.

Stay updated on generic Trikafta availability

Every patient deserves affordable and safe cystic fibrosis care. Prices are finally moving toward what people can manage. With the Bangladesh generic about to become available soon, you can plan treatment with less uncertainty and more control.

Write to us for latest updates on the launch and availability of the generic version of Trikafta®.

About the Author - Aayyush Goyal has a background in healthcare consulting and pharmaceutical supply chains, with over a decade of experience in drug pricing, regulatory policy, and patient rights. He has advised patients, advocacy groups, and healthcare providers across 40+ countries on safe and compliant access to essential medicines. Through MedsPartner, Aayyush has overseen more than 30,000 successful patient deliveries worldwide, ensuring affordability without compromising safety or legality. He is a recognized advocate for ethical sourcing, generic access, and cross-border care solutions, and has contributed insights on global drug access in healthcare forums, media publications, and patient support networks.