Generic Everolimus (Afinitor®) - International Purchase & Savings Guide 2026

Summary - This blog explores affordable access to generic Everolimus for people living with kidney cancer, breast cancer, neuroendocrine tumors, and tuberous sclerosis complex. Through personal import of Everolimus via MedsPartner, patients can now save over 98% in costs compared to U.S. prices of branded Afinitor®, and upto 75% even over US generics.

For many people living with advanced kidney cancer, hormone receptor-positive breast cancer, neuroendocrine tumors, or tuberous sclerosis complex, specialty drug costs often become the deciding factor in whether and which treatment becomes feasible.

Afinitor®, a targeted cancer therapy, carries an enormous price tag of roughly $19K per month in the United States. Though the drug extends progression-free survival and controls tumor growth, the cost puts it out of reach for many across the globe.

Accessing quality-assured generic Everolimus from FDA and EMA-approved manufacturers changes this situation entirely. Through MedsPartner's compliant personal import service, you can access the same medicine at less than 5% of the cost of branded Afinitor®, while being just as safe, effective, and practical for treatment continuity in the long run.

If you or your loved one has been written a prescription for Afinitor®/Everolimus, and are exploring ways to make the treatment affordable, tired of paying high copays, or stuck with an insurance that doesn’t make things any easier, you are at the right place. 

Here’s how you too can access quality everolimus from MedsPartner at a fraction of the cost, without burning holes in your pocket.

What is Everolimus (Afinitor®) and how does it work - Mechanism of action

Everolimus is a targeted cancer drug that blocks mTOR, a protein that controls cell growth and division. 

The mTOR pathway is particularly active in cancer cells - a mechanism that allows tumors to grow rapidly. Blocking mTOR specifically slows tumor growth and proliferation, unlike chemotherapy, which attacks all fast-growing cells.

This anticancer drug is used to treat advanced kidney cancer, specific types of breast cancer, certain neuroendocrine tumors affecting the pancreas, digestive system, or lungs, and tuberous sclerosis complex (TSC).

Speaking of clinical evidence, Everolimus more than doubled disease-free progression time (in months) in kidney cancer patients, as compared to placebo. A similar outcome has been seen for pancreatic neuroendocrine tumors, where it more than doubled the time patients remained progression-free - from 4.6 months to 11 months.

Recent updates on Everolimus and Afinitor®

FDA approves extended-release Everolimus capsules for tuberous sclerosis

In January 2025, Amneal received FDA approval for everolimus tablets for oral suspension for children and adults with tuberous sclerosis complex (TSC)‑related brain tumors (SEGA). This child‑friendly formulation is based on Afinitor Disperz® and adds another trusted generic option to the market, offering hope to families and caregivers.

Everolimus as part of combination therapy

1. Kidney Cancer - A phase 2 trial presented showed everolimus plus lenvatinib kept kidney cancer stable for ~15.7 months compared to 10.2 months with cabozantinib alone, in patients who'd already tried immunotherapy without success.
   
   
2. Pancreatic and intestinal cancers - Another 2025 study showed that everolimus plus lanreotide worked much better than lanreotide alone as first‑line treatment for well‑differentiated gastroenteropancreatic neuroendocrine tumors. The combination extended the time before tumors grew by about 30 months on average, and researchers think it could become a new and standard first-line option for these slow‑growing cancers.

How much does Everolimus cost - Brand Afinitor® vs generic options

Everolimus prices vary widely depending on where you source it, even within the United States. 

Below are costs for one month's supply (28 tablets) -

Cost comparison - 10 mg strength of Afinitor®/everolimus

Cost Comparison - 5 mg strength of Afinitor®/everolimus

Although US everolimus generics cost less than branded Afinitor®, monthly bills still range from $4,000 to $12,000. This becomes a heavy burden, especially for patients taking 10 mg daily continuously, often for months or years on end.

MedsPartner is a generic medicine supplier that ships quality-assured, affordable, critical cancer medicines to patients with a valid prescription, in over 40+ countries. Tagged at just $350 for a monthly dose of 10 mg, or $250 for 5 mg, we source medicines from FDA/EMA-approved manufacturers and provide free consultations to help navigate your country's regulations and secure a steady supply.

For someone on a 10 mg daily dosage of Everolimus, the cost translates to $4,200 per year through MedsPartner, versus $236,000 for branded US retail. That's 98% savings, annually.

Patients and caregivers are saving $231,800 annually by importing everolimus through MedsPartner.

Why is Afinitor® so expensive - even with insurance?

In the United States, a 28-day supply of Afinitor® costs approximately $18,413 to $19,260, depending on strength, totaling roughly $230,000 annually. Most insurance plans place Everolimus in specialty tiers where patients pay coinsurance rather than a fixed copay. Out-of-pocket costs vary significantly, depending on your plan.

Novartis held exclusive patent rights until patents began expiring between 2025 and 2028. Without competition from generics during this period, prices remain high. Everolimus also received orphan drug designation for tuberous sclerosis complex, allowing manufacturers to charge higher prices because fewer patients need the medication.

Many insurers require prior authorization before covering Everolimus. The Novartis Oncology Universal Co-Pay Program allows eligible patients with private insurance to pay $0 per month, with Novartis covering up to $15,000 per calendar year.

Outside the United States, access varies by country. Some nations approve Everolimus but don't fund it through public health systems. One may even need extensive approvals that drag on for months. Chances are, the medicine isn't stocked in hospital pharmacies at all. 

Due to these complications, patients find it extremely difficult to access medicines their doctors prescribe, and more importantly, when they actually need it. This is when families start exploring alternative routes, including personal import of generic everolimus, to obtain the same medicine affordably, without the jarring treatment interruptions or uncertainty.

Is it legal to import generic Everolimus?

Yes, also called Named Patient Access, importing medicines for personal use is legal in most countries that recognize that when local medicine prices are unaffordable or drugs aren't available, patients need options.

Here's how personal import works - You need a legitimate prescription from your doctor for Everolimus. The medicine has to be for your own treatment - not for resale or giving to others. Most countries allow you to import 1-3 months' worth at a time. Your shipment needs proper paperwork - prescription copies, invoices, and manufacturer details for customs.

MedsPartner specializes in navigating these country-specific regulations. We offer free consultation to personally guide you through your local requirements and ensure every shipment complies with your country's rules and customs.

How MedsPartner helped a family in New Zealand access affordable Everolimus

Sally from New Zealand needed Everolimus for her progressive pancreatic neuroendocrine tumor. However, accessing it was not so straightforward.

In New Zealand, funding for everolimus is managed by PHARMAC and is typically restricted to specific indications under Special Authority criteria. Approval can take several months, and in some cases, patients are found ineligible altogether. Meanwhile, private pharmacies were quoting Afinitor® at approximately NZD 9,000–10,000 per month, placing it well beyond what Sarah’s family could sustainably afford.

That’s when Sarah’s son discovered MedsPartner through an online search and booked a free consultation. We explained how New Zealand’s personal importation regulations work and outlined a compliant, faster pathway to access treatment.

With their oncologist’s prescription and MedsPartner’s personalised, country-specific documentation support, the family was able to procure quality-assured everolimus, sourced and delivered to their home in Auckland within 14 days, complete with customs clearance, for just USD 250 per month. This amounted to less than 5% of the local private price of branded Afinitor®.

“The process was clear, reassuring, and helped us continue treatment without financial panic,” said Sarah’s son.

Answering your Questions on Everolimus and affordable access

Q1. What if my insurance denies coverage for Afinitor®?

A. Insurance denial or unaffordable copays are extremely common with Everolimus due to its specialty classification. You have several options -

• Appeal with your doctor's support - Provide documentation of medical necessity and prior treatment failures
• Apply for manufacturer assistance - Novartis offers the Oncology Universal Co-pay Program for eligible commercially insured US patients, potentially reducing copays to $0-$25, with Novartis paying up to $15,000 annually
• Explore foundation support - Organizations like HealthWell Foundation occasionally have funds for specific cancers
• Personal import of generic Everolimus - When the above options fail or aren't available, MedsPartner provides legal access to affordable generics, saving 95%+ compared to US retail prices

Q2. What if my Afinitor® copays are too high even with insurance?

A. Specialty tier copays for everolimus/Afinitor® often hit 25-50% coinsurance, and thousands in monthly out-of-pocket costs. Novartis copay cards cap at $15K/year for commercial insurance only. When those run out or don't apply, MedsPartner delivers the equivalent medicine for ~$250-350/month in total, without the copay/insurance hassle.

Q3. How can I trust the quality of generic Everolimus from MedsPartner?

A. MedsPartner sources approved generics only from FDA/EMA-approved manufacturers. The generics have to prove bioequivalence to the branded drug (same active ingredient and similar therapeutic action) to be approved by local regulators. Additionally, we select our suppliers after thorough quality checks and run strict checks on each batch before processing your order. This ensures that you get high-quality, affordable Everolimus through MedsPartner.

Q4. How does the personal import process work through MedsPartner?

A. The process is straightforward -

1.  Upload your prescription - Visit MedsPartner's Everolimus page and securely upload your doctor's prescription specifying dose, strength, and duration

2. Document verification - Our team verifies prescription validity and checks your country's specific import regulations

3. Receive quotation - We provide a transparent price quote, including medicine cost, international shipping, and any applicable fees

4. Payment and sourcing - Upon payment, we source your generic Everolimus from FDA/EMA-approved manufacturers, conducting batch quality verification

5. Documentation preparation - All required customs paperwork is prepared specifically for your country

6. Tracked shipment - Your medicine ships via reliable courier (DHL/FedEx) with end-to-end tracking

7. Delivery to your door - Typically arrives within 7-14 days, depending on destination

Q5. I'm a doctor - how can I help my patient access affordable Everolimus?

A. Doctors can support patients by providing clear prescriptions for Everolimus specifying the indication, dose, and duration of treatment. You can add a short medical note for customs. For further support, you can email support@medspartner.com and avail our personalised assistance.
Our team of qualified pharmacists verifies prescriptions, sources quality generics, handles customs and compliance, and ships everolimus directly to the patient, all so you control the treatment plan while we solve the cost and access barriers.

Q6. Is Everolimus/Afinitor® chemotherapy?

A. No. Everolimus is a targeted therapy effective only for specific cancer types where the mTOR pathway plays a key role.

It's neither broad-spectrum (unlike chemotherapy) nor effective for most other cancers. Your oncologist determines appropriateness based on your cancer type, molecular characteristics, and prior treatments.

Q7. Where to buy generic Everolimus (Afinitor®) online safely?

A. With a TrustPilot rating of 4.4 out of 5, MedsPartner specializes in legal personal import of FDA/EMA-approved generic medicines for cancer patients worldwide. We supply quality-assured everolimus starting at $250/month, provide country-specific import guidance, and offer free consultations to ensure compliance with local laws. Visit our website to know more and place an order.

Get Affordable Everolimus Without the Wait

Everolimus offers hope and extended survival for patients with kidney cancer, breast cancer, neuroendocrine tumors, and tuberous sclerosis. However, the price of branded Afinitor®, together with the lengthy approvals for insurance, high copays, and eligibility norms of patient support programs, often makes it feel out of reach.

That's where generic everolimus from FDA/EMA-approved manufacturers changes everything. Through MedsPartner's personal import service, patients get the exact same medicine for 95-98% less cost, home-delivered within 7 - 14 days of ordering – helping families support and sustain months or years of consistent treatment.

Looking to access Everolimus at an affordable price? Need guidance on personal importation?

Write to us today to get started. Or order everolimus here by uploading your prescription, and avail a free consultation where we walk you through your country's import rules with clear pricing upfront.

About the Author - Atul Goyal combines operational insight with a strong understanding of global healthcare systems - honed through years of managing complex pharmaceutical supply chains. At MedsPartner - he leads efforts to streamline international medicine deliveries, balancing efficiency, compliance, and patient affordability. His experience spans - logistics, pricing strategy, and regulatory frameworks, enabling him to navigate the evolving landscape of global medicine access with both precision and empathy.